منابع مشابه
Stem Cell Organoid Engineering
Organoid systems leverage the self-organizing properties of stem cells to create diverse multicellular tissue proxies. Most organoid models only represent single or partial components of a tissue, and it is often difficult to control the cell type, organization, and cell-cell/cell-matrix interactions within these systems. Herein, we discuss basic approaches to generate stem cell-based organoids...
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R ecent developments in stem cell research and genomics have made it possible to grow mini-organs, socalled organoids, in culture. Organoids are self-assembling three-dimensional structures that closely resemble the architecture and function of real organs and are seen as one of the most significant developments in stem cell research with a wide range of applications in research and in the clin...
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Recent technical advances in the stem cell field have enabled the in vitro generation of complex structures resembling whole organs termed organoids. Most of these approaches employ three-dimensional (3D) culture systems that allow stem cell-derived or tissue progenitor cells to self-organize into 3D structures. These systems evolved, methodologically and conceptually, from classical reaggregat...
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ژورنال
عنوان ژورنال: Nature Methods
سال: 2017
ISSN: 1548-7091,1548-7105
DOI: 10.1038/nmeth.4362